Primary Identifier | IPR037000 | Type | Homologous_superfamily |
Short Name | Ski_DNA-bd_sf |
description | The c-ski proto-oncogene has been shown to influence proliferation, morphological transformation and myogenic differentiation []. It may play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Sno, a Ski proto-oncogene homologue, is expressed in two isoforms and plays a role in the response to proliferation stimuli.Ski is a multidomain protein that includes a domain bearing high sequence similarity with the retinal determination protein Dachshund []. This conserved domain contains a DNA binding motif []. |