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Protein Domain : Growth factor receptor-bound protein 7

Primary Identifier  IPR035032 Type  Family
Short Name  Grb7
description  Grb7 (growth factor receptor bound protein 7) is an adapter protein mediating signal transduction from multiple cell surface receptors to diverse downstream pathways [, , ]. It contains a Ras-associating (RA) domain, a pleckstrin-homology (PH) domain, a family-specific BPS (between PH and SH2) region and a C-terminal SH2 domain [, ]. It can bind to the epidermal growth factor receptor (EGFR, erbB1) viathe SH2 domain [].

0 Child Features

1 Parent Features

3 Protein Domain Regions