| Primary Identifier | IPR040647 | Type | Domain |
| Short Name | SPIN-DOC_Znf-C2H2 |
| description | This is a zinc finger domain C2H2 type which can be found in SPIN1 docking protein (SPIN-DOC). SPIN-DOC is a Spindlin1 (SPIN1) regulator that directly binds and strongly disrupts its histone methylation reading ability, causing it to disassociate from chromatin []. Proteins containing this domain also include Epm2aip1, which is a glycogen synthase (GS)-associated protein. In the absence of Epm2aip1, the sensitivity of the liver to insulin, in which GS is a principal actor, is impaired []. |
