| Primary Identifier | IPR015845 | Type | Family |
| Short Name | Mas1 |
| description | Several agrobacteria cause neoplastic diseases in plants, including crown gall disease (Agrobacterium tumefaciens) and hairy root disease (Agrobacterium rhizogenes). The mechanism involves transfer via infective plasmids and subsequent expression of both oncogenes and genes for the synthesis of opines, which can be specifically used as nutrients by the invading bacteria []. Opines are low molecular weight amino acid and sugar phosphate derivatives, e.g., octopine, agropine, and mannopine. The proteins in this group are products of the mas1genes (and homologues) encoding the reductase that produces mannopine from deoxyfructosylglutamine. Subsequently, mannopine can be lactonized to form agropine. The C-terminal short chain dehydrogenase domain is coupled with an N-terminal phosphoglycerate mutase family domain (), the role of which is unknown []. Sequences reported from Ti plasmid pTiC58 are missing half [, ]or all of the N-terminal domain. |
