| Primary Identifier | IPR035508 | Type | Family |
| Short Name | STAC1 |
| description | Stac proteins are putative adaptor proteins that contain a cysteine-rich C1 domain and one or two SH3 domains at the C terminus. There are three mammalian members: Stac1, Stac2, and Stac3. Stac1 and Stac3 contain two SH3 domains while Stac2 contains a single SH3 domain at the C terminus. They regulate voltage-gated calcium channel (CaV) trafficking and function [, ]. This entry represents Stac1. Stac1 and Stac2 have been found to be expressed differently in mature dorsal root ganglia (DRG) neurons. Stac1 is mainly expressed in peptidergic neurons while Stac2 is found in a subset of nonpeptidergic and all trkB+ neurons []. |
