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Protein Domain : N-formyltransferase dimerization C-terminal domain

Primary Identifier  IPR040660 Type  Domain
Short Name  N_formyltrans_C
description  This is the C-terminal domain of N-formyltransferase from Francisella tularensis. N-formylated sugars are observed on O-antigens of pathogenic Gram-negative bacteria. This C-terminal domain is responsible for dimerization. In particular, the beta hairpin motif present in the domain helps create a subunit-subunit interface. The dimeric interface is characterized by a hydrophobic patch formed by Ile 195, Leu 197, Val 201, Met 203, Ile 207, Phe 223, Val 231, Val 233, Leu 235, and Leu 237 from both monomers [].

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