Primary Identifier | IPR039675 | Type | Family |
Short Name | CILP1/CILP2 |
description | This entry includes cartilage intermediate layer proteins 1 (CILP1) and 2 (CILP2). CILP1 acts as a modulator of lumbar disc disease susceptibility []. CILP1 interferes with pro-fibrotic TGFbeta signalling and is a mediator of cardiac extracellular matrix remodeling []. CILP2 is present in human articular cartilage and may be associated with collagen VI containing suprastructures []. |