| Primary Identifier | IPR039679 | Type | Family |
| Short Name | NRBF2 |
| description | Nuclear receptor-binding factor 2 (NRBF2) plays an essential role in autophagy, the cellular pathway that degrades long-lived proteins and other cytoplasmic contents through lysosomes. NRBF2 binds Atg14L - a Beclin-binding protein - directly via the MIT domain and enhances Atg14L-linked Vps34 kinase (a class III phosphatidylinositol-3 kinase) activity and autophagy induction [, ]. |
