Primary Identifier | IPR039500 | Type | Domain |
Short Name | EVA1_dom |
description | This entry represents the EVA1 domain found in a group of proteins, including EVA1A/B/C. EVA1A, also known as TMEM166, regulates cell autophagy and apoptosis [, ].This domain can be found in the C terminus of the human EVA1C, which serves as the Slit receptor that may mediate neural circuit formation in the developing nervous system. The EVA1C gene is located within the Down syndrome critical region (21q21-21q22.3) []. |