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Protein Domain : Developmental pluripotency-associated protein 2/4

Primary Identifier  IPR039590 Type  Family
Short Name  Dppa2/4
description  Developmental pluripotency-associated protein 2 (Dppa2, also known as ECAT15-2) and Dppa4 (also known as ECAT15-1) have a common DNA binding domain known as the SAP motif. Dppa2 has been found to bind to the regulatory region of Nkx2-5 in embryonic stem (ES) cells []. Dppa4 has been found to bind to both DNA and histone H3 necessary for the chromatin structure resistance to MNase and for the proper localization of Dppa4 in ES cell nuclei [].

2 Child Features

0 Parent Features

6 Protein Domain Regions