Primary Identifier | IPR035774 | Type | Domain |
Short Name | SPRY_RSPRY1 |
description | This SPRY domain is found at the N terminus of RING finger domains which are present in a variety of functionally distinct proteins and are known to be involved in protein-protein and protein-DNA interactions. The RING-finger domain is a type of Zn-finger that binds two Zn atoms.The role of RSPRY1 (RING finger and SPRY domain-containing protein 1) is not known, but it may have a role in bone development. Mutations in RSPRY1 cause skeletal dysplasia []. |