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Protein Domain : CUE domain-containing protein 2, CUE domain

Primary Identifier  IPR039805 Type  Domain
Short Name  CUE_CUED2
description  CUEDC2 is a novel negative regulator of progesterone receptor (PR) and functions to promote the progesterone-induced PR degradation by the ubiquitin-proteasome pathway []. It also acts as the regulator of JAK1/STAT3 signaling through inhibiting cytokine-induced phosphorylation of JAK1 and STAT3 and the subsequent STAT3 transcriptional activity []. This entry represents the CUE domain found in CUEDC2.

0 Child Features

0 Parent Features

5 Protein Domain Regions