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Protein Domain : Pinin

Primary Identifier  IPR039853 Type  Family
Short Name  Pinin
description  Pinin (also known as memA and nuclear protein SDK3) is localised at the desmosomes and is implicated in anchoring intermediate filaments to the desmosomal plaque []. It is also a transcriptional activator, binding to the the E-box 1 core sequence of the E-cadherin promoter gene []. Pinin is also found in nuclear 'speckles' where it is also an auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs [], and a component of the PSAP complex [].

0 Child Features

0 Parent Features

3 Protein Domain Regions