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Protein Domain : Myogenic factor

Primary Identifier  IPR039704 Type  Family
Short Name  Myogenic_factor
description  Myogenic factors are involved in muscle differentiation, inducing fibroblasts to differentiate into myoblasts. Myogenic factor 5 (Myf5) is responsible for directing cells to the skeletal myocyte lineage during development []. Myf5 and Myod (myoblast determination protein 1) are predominantly expressed in proliferating myoblasts while Myf4 and Myf6 are involved in differentiation of myotubes []. Myogenin (MYOG) is a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy [, ].

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7 Protein Domain Regions