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Protein Domain : Heat shock factor protein 2

Primary Identifier  IPR027712 Type  Family
Short Name  HSF2
description  Four heat shock factor proteins (HSFs) have been identified in vertebrates (HSF1-4) []. HSF2 is localised to the cytoplasm duringnormal growth and moves to the nucleus upon activation [], where it specifically binds heat shock promoter elements (HSE) and activates transcription. HSF2 may not be directly involved in the stress response, but rather in cell differentiation and development [, ]. HSF1 and HSF2 can form heterotrimers, which could be a mechanism regulating transcription [].

0 Child Features

1 Parent Features

4 Protein Domain Regions