Primary Identifier | IPR037898 | Type | Family |
Short Name | NudC_fam |
description | This family includes NudC (nuclear distribution gene C), NudC-like (NudCL) [], NudC-like 2/NudC domain-containing protein 2 (NudCL2/NUDCD2)[], NudC domain-containing protein 3, and NudC domain protein BOBBER from plants []. All members of the NudC family share a conserved p23 domain, which possesses chaperone activity both in conjunction with and independently of heat shock protein 90 (Hsp90) []. NudC proteins play multiple roles in cell cycle progression, cell migration, inflammatory response, platelet production, carcinogenesis [, ]. |