| Primary Identifier | IPR015757 | Type | Family |
| Short Name | Calcineur_B |
| description | Calcineurin is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase that plays an essential role in the T cell activation pathway. Calcineurin and Nuclear factor of Activated T-cell (NFAT) proteins have been shown to participate in signalling cascades that govern the development and function of the immune, nervous, cardiovascular and musculoskeletal systems []. Calcineurin is a heterodimeric protein consisting of: i) a catalytic subunit calcineurin A, which contains an active site dinuclear metal centre, and ii) a tightly associated, myristoylated, Ca(2+)-binding subunit, calcineurin B []. |
