| Primary Identifier | IPR001179 | Type | Domain |
| Short Name | PPIase_FKBP_dom |
| description | FKBP-type peptidylprolyl isomerases () in vertebrates, are receptors for the two immunosuppressants, FK506 and rapamycin. The drugs inhibit T cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. Peptidylprolyl isomerases accelerate protein folding by catalysing the cis-trans isomerisation of proline imidic peptide bonds in oligopeptides. These proteins are found in a variety of organisms [].This entry represents a domain found in FKBP-type peptidylprolyl isomerases. |
