| Primary Identifier | IPR037193 | Type | Homologous_superfamily |
| Short Name | GDNF_alpha |
| description | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) receptors are potent survival factors for sympathetic, sensory and central nervous system neurons [, ]. GDNF and neurturin promote neuronal survival by signalling through similar multicomponent receptors that consist of a common receptor tyrosine kinase and a member of a GPI-linked family of receptors that determines ligand specificity [].Structurally, GDNF is composed of five helices with an irregular disulfide-linked array. It is topologically similar to the fungal elicitin fold (). |
