| Primary Identifier | IPR035491 | Type | Domain |
| Short Name | ARHGAP12_SH3 |
| description | Rho GTPase-activating proteins (RhoGAPs or ARHGAPs) bind to Rho proteins and enhance the hydrolysis rates of bound GTP. ARHGAP12 has been shown to display GAP activity towards Rac1. It plays a role in regulating hepatocyte growth factor (HGF)-driven cell growth and invasiveness []. It contains SH3, WW, Pleckstin homology (PH), and RhoGAP domains []. This entry represents the SH3 domain of ARHGAP12. |
