| Primary Identifier | IPR035499 | Type | Domain |
| Short Name | Caskin2_SH3 |
| description | Caskin2 is a multidomain adaptor protein that contains six ankyrin repeats, a single SH3 domain, tandem sterile alpha motif (SAM) domains, and a long disordered proline-rich region. It shares a domain architecture with Caskin1, but does not bind CASK [, ]. The CASKIN2 SH3 domain has two substitutions that prevent it from binding typical polyproline ligands, which indicates that it could be a nonfunctional remnant in this protein []. |
