Primary Identifier | IPR035511 | Type | Domain |
Short Name | SH3YL1_SH3 |
description | SH3YL1 (SH3 domain-containing YSC84-like protein 1) localizes to the plasma membrane and is required for dorsal ruffle formation. It binds phosphoinositides (PIs) with high affinity through its N-terminal SYLF domain []. In addition, SH3YL1 contains a C-terminal SH3 domain which has been reported to bind to N-WASP, dynamin 2 and SHIP2 [, ].This entry represents the SH3 domain of SH3YL1. |