| Primary Identifier | IPR035612 | Type | Domain |
| Short Name | SH3RF3_SH3_3 |
| description | This entry represents the third SH3 domain, located in the middle, of SH3RF3.SH3RF3 (also known as POSH2) is a scaffold protein with E3 ubiquitin-protein ligase activity []. It was identified in the screen for interacting partners of p21-activated kinase 2 (PAK2). It may play a role in regulating JNK mediated apoptosis in certain conditions []. It also interacts with GTP-loaded Rac1 []. SH3RF3 is highly homologous to SH3RF1; it also contains an N-terminal RING finger domain and four SH3 domains. |
