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Protein Domain : SAM and SH3 domain-containing protein 3, SH3 domain

Primary Identifier  IPR035721 Type  Domain
Short Name  SASH3_SH3
description  SASH3, also called SLY/SLY1 (SH3-domain containing protein expressed in lymphocytes), is expressed exclusively in lymhocytes and is essential in the full activation of adaptive immunity []. It is involved in the signaling of T cell receptors []. It was the first described member of the SLY family of proteins, which are adaptor proteins containing a central conserved region with a bipartite nuclear localization signal (NLS) as well as SAM (sterile alpha motif) and SH3 domains [].This entry represents the SH3 domain of SASH3.

0 Child Features

1 Parent Features

1 Protein Domain Regions