Primary Identifier | IPR035751 | Type | Domain |
Short Name | Yes_SH3 |
description | Yes kinase (also known as c-Yes) is a member of the Src family of nonreceptor tyrosine kinases []. It is involved in the regulation of cell division, differentiation, survival, motility, adhesion, spreading and vesicular transport []. It plays an important role in epiboly during early development in zebrafish []. Yes kinase contains an SH4 motif responsible for membrane localization, a Unique domain, followed by SH3 and SH2 domains, the protein tyrosine kinases or SH1 domain, and a carboxy terminal regulatory region []. This entry represents the SH3 domain of Yes tyrosine kinase. |