| Primary Identifier | IPR037430 | Type | Domain |
| Short Name | SNX4_BAR |
| description | SNX4 is involved in recycling traffic from the sorting endosome (post-Golgi endosome) back to the late Golgi. It shows a similar domain architecture as SNX1-2, among others, containing a Bin/Amphiphysin/Rvs (BAR) domain, which detects membrane curvature, C-terminal to the PX domain []. SNX4 is implicated in the regulation of plasma membrane receptor trafficking and interacts with receptors for EGF, insulin, platelet-derived growth factor and the long form of the leptin receptor [].This entry represents the BAR domain of SNX4 from Metazoa. BAR domains are dimerization, lipid binding and curvature sensing modules found in many different proteins with diverse functions []. |
