| Primary Identifier | IPR037479 | Type | Family |
| Short Name | Tauto_MSAD |
| description | Members of the tautomerase superfamily (TSF) are characterised by a beta-α-β building block and a catalytic amino terminal proline [, ]. There are five known TSF families, which are named for the first characterised member [].This entry represents the malonate semialdehyde decarboxylase (MSAD) family []. MSAD is part of a bacterial pathway for the degradation of the soil fumigant known as 1,3-dichloropropene []. There are five homologues identified, including YusQ/YodA/YrdN from Bacillus subtilis, IolK from Lactobacillus casei strain BL23, and Bp4401 from Burkholderia phymatum. IolK was found in a degradative pathway for myo-inositol, but its disruption does not affect growth or myo-inositol utilization []. Bp4401 has a modest hydratase activity. YrdN, YodA, and IolK have comparable decarboxylase and hydratase activities, but this activity is missing in YusQ and Bp4401 []. |
