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Protein Domain : D-amino acid oxidase activator

Primary Identifier  IPR027929 Type  Family
Short Name  DAOA
description  Members of this family function as activators of D-amino acid oxidase. This enzyme catalyzes the oxidative deamination of D-3,4-dihydroxyphenylalanine (D-DOPA) and D-serine - a precursor of dopamine and a participant in glutamatergic transmission, respectively []. Variation in the DAO activator gene have been associated with bipolar disorder and major depression [], although other studies have cast doubt on such a link [].

0 Child Features

0 Parent Features

5 Protein Domain Regions