Primary Identifier | IPR027929 | Type | Family |
Short Name | DAOA |
description | Members of this family function as activators of D-amino acid oxidase. This enzyme catalyzes the oxidative deamination of D-3,4-dihydroxyphenylalanine (D-DOPA) and D-serine - a precursor of dopamine and a participant in glutamatergic transmission, respectively []. Variation in the DAO activator gene have been associated with bipolar disorder and major depression [], although other studies have cast doubt on such a link []. |