| Primary Identifier | IPR039943 | Type | Family |
| Short Name | ICOS |
| description | ICOS is an inducible T-cell co-stimulator with homology to CD28 []. CD28 and ICOS function similarly during expansion, survival and differentiation of T cells. They are necessary for proper IgG responses. However, CD28 induces IL-2 production, while ICOS is more potent in the induction of IL-10 production []. |
