| Primary Identifier | IPR037312 | Type | Domain |
| Short Name | PKC-like_HR1 |
| description | This entry represents the second HR1 domain found in fungal PKC-like proteins including Pkc1p from Saccharomyces cerevisiae, and Pck1p and Pck2p from Schizosaccharomyces pombe. The yeast PKC-like proteins play a critical role in regulating cell wall biosynthesis and maintaining cell wall integrity []. They contain two HR1 domains, C2 and C1 domains, and a kinase domain. HR1 domains are anti-parallel coiled-coil (ACC) domains that bind small GTPases from the Rho family []. The HR1 domains of Pck1p and Pck2p interact with GTP-bound Rho1p and Rho2p []. |
