| Primary Identifier | IPR035512 | Type | Family |
| Short Name | CASS4 |
| description | CASS4, also known as HEPL, is a Cas family member that regulates FAK and cell spreading [].The CAS (Crk-Associated Substrate) protein family is a group of scaffolding proteins that play important modulatory roles in both normal and pathological cell growth regulation. They contain an N-terminal Src homology 3 (SH3) domain and a substrate domain (SD). The SD contains a large number of YxxP motifs, which when phosphorylated by Src-family kinases provide canonical binding sites for proteins containing SH2 domains such as Crk, Crk-L, CRKII []. |
