| Primary Identifier | IPR033925 | Type | Domain |
| Short Name | Rad51_DMC1_RadA |
| description | This domain is found at the C terminus of the DNA repair and recombination protein Rad51 and some Rad51-like proteins. It is critical for DNA binding []. Rad51 is a homologue of the bacterial RecA protein. Rad51 and RecA share a core ATPase domain.Rad51-like genes form two separate groups (RAD-alpha and RAD-beta), each of which contains both archaeal and eukaryotic members []. This group of recombinases includes the eukaryotic proteins Rad51, Rad57, the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group []. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as Rad55/57 [, ]. |
