Primary Identifier | IPR035097 | Type | Homologous_superfamily |
Short Name | M29_N-terminal |
description | This superfamily represents a domain found in a group of metallopeptidases that belong to MEROPS peptidase family M29 (aminopeptidase T family, clan M-), and that includes AmpS and AmpT.Staphylococcus aureus aminopeptidase S (AmpS) has been named for its predicted, but experimentally untested, aminopeptidase activity. The enzyme is homologous to biochemically characterized aminopeptidases. It is a dimeric protein with a very unusual, elongated shape and a large internal cavity []. Aminopeptidase T (AmpT) from Thermus thermophilus is an homologue of AmpS. AmpT, like AmpS, can be divided into an N-terminal domain and a C-terminal domain, with a flexible hinge between them []. This entry represent the N-terminal domain. |