| Primary Identifier | IPR001573 | Type | Domain |
| Short Name | AKAP_WSK |
| description | The AKAP CaM-binding motif (also known as the WSK motif) is short motif, named after three conserved residues found in the WXSXK motif, found in protein kinase A anchoring proteins. The A kinase-anchoring proteins AKAP-5 and AKAP-12 (Gravin) bind calmodulin (CaM), a Ca(2+)-sensing protein that is expressed in all eukaryotic cells and mediates many essential processes driven by Ca(2+), including long-term changes in synaptic connections in the brain, apoptosis, and immune responses. The AKAP CaM-binding motif contains hydrophobic amino acids in a 1-4-7-8 pattern within an helix []. |
