Primary Identifier | IPR031183 | Type | Family |
Short Name | Glypican-6 |
description | Glypicans are heparan sulphate proteoglycans (HSPGs) attached to the cell membrane by a glycosylphosphatidylinositol (GPI) anchor that interact with various extracellular growth factors and receptors. Six members (GPC1-6) are known in vertebrates [].Glypican-6 has a role in endochondral ossification and skeletal growth []. It also enhances migration and invasion of cancer cells through WNT5A signalling []. |