| Primary Identifier | IPR013859 | Type | Domain |
| Short Name | Ssr4_N |
| description | This is the N-terminal domain of the SWI/SNF and RSC complexes subunit Ssr4 from S. pombe, a member of the chromatin structure remodeling complex (RSC) and the SWI/SNF complex [, ]. RSC is involved in transcription regulation and nucleosome positioning which controls, particularly, membrane and organelle development genes. The ATP-dependent chromatin remodelling complex SWI/SNF is required for the positive and negative regulation of gene expression of a large number of genes through the regulation of nucleosome remodelling [].The structure of this domain revealed that it has a novel fold comprising an antiparallel β-sheet of seven strands with α-helices on one side and random coil on the other []. It contains the highly conserved motif WxxxxxPxxGxxxxxxxxxxxxxxxDG. |
