Primary Identifier | IPR011207 | Type | Family |
Short Name | Orthopox_F1 |
description | The poxvirus F1 family members are related to Vaccinia virus protein F1L, which interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells. F1L suppresses mitochondrial-dependent apoptosis by binding to the BH3 domain of host BAK and prevents BAK from binding active BAX [, ]. |