|  Help  |  About  |  Contact Us

Protein Domain : Ubiquitin thioesterase otulin

Primary Identifier  IPR023237 Type  Family
Short Name  Otulin
description  Otulin (also known as FAM105B) belongs to the ovarian tumour (OTU) deubiquitinases (DUBs) family []. It specifically removes linear ('Met-1'-linked) polyubiquitin chains to substrates and acts as a regulator of angiogenesis and innate immune response []. It associates with the LUBAC complex via direct interaction with RNF31 and counteracts its action by cleaving linear polyubiquitin chains to substrates [].
Paste the following link
Lists
This ProteinDomain isn't in any lists. Upload a list.

0 Child Features

1 Parent Features

Trail: ProteinDomain

7 Protein Domain Regions

Trail: ProteinDomain




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom