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Protein Domain : COMPASS component Swd2/WDR82

Primary Identifier  IPR037867 Type  Family
Short Name  Swd2/WDR82
description  This entry includes Swd2 from yeasts and WDR82 from animals. They are part of the Set1/COMPASS complex [].Besides being part of the Set1/COMPASS complex, Swd2 is also a component of the cleavage and polyadenylation factor (CPF) complex and its subcomplex APT [, , ].The COMPASS (Complex Proteins Associated with Set1 or Set1C) is the yeast homologue ofthe human MLL complex, which is required for mono-, di-, and trimethylation of lysine 4 of histone H3 []. It is required in telomeric transcriptional silencing []. The complex consists of Set1, Bre2, Spp1, Sdc1, Shg1, Swd1, Swd2, and Swd3 [, ].

0 Child Features

0 Parent Features

4 Protein Domain Regions