| Primary Identifier | IPR037850 | Type | Family |
| Short Name | RBBP5/Swd1 |
| description | This entry includes RBBP5 from animals, RBL from plants and Swd1 from yeasts. Swd1 is a component of the SET1C/COMPASS complex, a complex that methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres [, ].Retinoblastoma-binding protein 5 (RBBP5) is important for development in embryonic stem cells, regulating gene induction and H3 'Lys-4' methylation at key developmental loci []. It is a component of the SET1 histone methyltransferase complex [], and methyltransferase-containing (COMPASS) complexes MLL1, MLL2/3 and MLL4 [, ].Arabidopsis RBL is also a component of a COMPASS-like complex that mediates histone H3 lysine-4 trimethylation to control floral transition and plant development []. |
