Primary Identifier | IPR013745 | Type | Family |
Short Name | Bit61/PRR5 |
description | This entry includes PRR5 (also known as PROTOR1) from animals, Bit61 and its paralogue-Bit2 from budding yeasts [, ]. They are part of the Target Of Rapamycin Complex 2 (TORC2) complex, which plays an essential role in signal transduction []. The mammalian TORC2 consists of mTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR [, , , , ]. The budding yeast TORC2 is composed of Avo1, Avo2, Tsc11, Lst8, Bit61, Slm, Slm2 and Tor2 [, ]. |