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Protein Domain : Myelin gene regulatory factor C-terminal domain 2

Primary Identifier  IPR025719 Type  Domain
Short Name  MYRF_C2
description  Myelin regulatory factor (Myrf) is a transcription regulator required in vertebrates for expression of central nervous system (CNS) myelin genes such as Mbp and Mog, thereby playing a central role in oligodendrocyte maturation and CNS myelination []. It is also required for the maintenance of expression of myelin genes and the mature oligodendrocytes identity in the adult CNS [, ]. A Caenorhabditis elegans orthologue, pqn-47, may function as a regulator of molting [], while a Dictyostelium orthologue has been described to regulate prestalk differentiation [].This domain is found at the C terminus of myelin regulatory factor. The function of the domain is not known.

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3 Protein Domain Regions