Primary Identifier | IPR011113 | Type | Domain |
Short Name | Rho_RNA-bd |
description | The Rho termination factor disengages newly transcribed RNA from its DNA template at certain, specific transcripts. It is thought that two copies of Rho bind to RNA and that Rho functions as a hexamer of protomers [].The Rho N-terminal domain consists of two subdomains: a three-helix bundle followed by a β-barrel. The β-barrel is an OB-type fold, which is found in a wide variety of single-stranded nucleic acid binding molecules that include cold shock proteins. An indented face on one side of this subdomain forms the primary RNA binding site of Rho []. |