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Protein Domain : Methyl-CpG-binding domain protein 3

Primary Identifier  IPR037965 Type  Family
Short Name  MBD3
description  Methyl-CpG-binding domain protein 3 (MBD3) is a transcriptional repressor and plays a role in gene silencing. It binds to DNA with a preference for sites containing methylated CpG dinucleotides but only as part of a complex [, ]. It forms a heterodimer with MBD2 []and is a component of the NuRD []and the MeCP1 []complexes.

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0 Parent Features

6 Protein Domain Regions