Primary Identifier | IPR037965 | Type | Family |
Short Name | MBD3 |
description | Methyl-CpG-binding domain protein 3 (MBD3) is a transcriptional repressor and plays a role in gene silencing. It binds to DNA with a preference for sites containing methylated CpG dinucleotides but only as part of a complex [, ]. It forms a heterodimer with MBD2 []and is a component of the NuRD []and the MeCP1 []complexes. |