| Primary Identifier | IPR037940 | Type | Domain |
| Short Name | MALT1_Death |
| description | MALT1 (MEROPS identifier C14.026) is a paracaspase that cleaves its substrates on the C-terminal side of an arginine residue []. It is a key regulator of antigen-induced NF-kappaB activation in the adaptive immune response []. Upon antigen stimulation MALT1 acts as a scaffold for a protein complex formed with CARMA1 (also known as CARD11) and Bcl10, the CBM complex. The CBM complex links AgR (antigen receptor) triggering to NF-kappaB activation [].This entry represents the death domain of MALT1. |
