Primary Identifier | IPR023394 | Type | Homologous_superfamily |
Short Name | Sec7_C_sf |
description | The Sec7 domain was named after the first protein found to contain such a region []. It has been shown to be linked with guanine nucleotide exchange function [, ]. The 3D structure of the domain displays several α-helices []. It was found to be associated with other domains involved in guanine nucleotide exchange (e.g., CDC25, Dbl) in mammalian factors [].This superfamily represents the alpha orthogonal structural domain which is found at the C terminus of the Sec7 domain (). |