| Primary Identifier | IPR035615 | Type | Family |
| Short Name | FiwA/Osa |
| description | Osa and FiwA are fertility inhibition factors (FIN), which are employed by plasmids to block import of rival plasmids []. Osa (oncogenic suppressive activity) of IncW group plasmid pSa gene inhibits the oncogenic properties of Agrobacterium tumefaciens. Osa is structurally similar to the ParB N-terminal domain/Srx superfamily of proteins: ParB acts in the bacterial and plasmid parABS partitioning systems []. Osa has been shown to have ATPase and DNAse activities, and can block T-DNA transfer into plants [, ]. FiwA is encoded by plasmid RP1 and blocks the transfer of plasmid R388 []. The gene product of Haemophilus influenzae p1056.10c also blocks T-DNA transfer []. |
