| Primary Identifier | IPR021031 | Type | Domain |
| Short Name | Hyphal-reg_cell_wall_N |
| description | This entry represents a conserved domain found at the N terminus of a number of fungal proteins. These proteins are largely annotated as being hyphally-regulated cell wall proteins that are induced in response to hyphal development. Proteins containing this domain include Hpf1 from budding yeasts and Hyr1 from Candida albicans. Hpf1 can reduce haziness in white wine []. Hyr1 is a GPI-anchored hyphal cell wall protein required for hyphal growth and virulence. It is involved in innate immune cell evasion through confering resistance to neutrophil killing [, ]. |
