| Primary Identifier | IPR045050 | Type | Family |
| Short Name | Synaptotagmin_plant |
| description | This entry represents a group of plant synaptotagmins and related proteins. In Arabodopsis, there are five members, SYT1-5. Structurally, they have a short uncleaved N-terminal signal peptide that overlaps a transmembrane (TM) domain, followed by a cytosolic variable region and two C-terminal C2 domains, C2A and C2B. Whereas C2A and C2B each bind phospholipids in a Ca2+-dependent manner, fold independently and act synergistically, C2B is essential for activity []. Arabidopsis SYT1, also known as SYTA, plays an important role in maintaining plasma membrane integrity during freezing and osmotic stresses [, ]. It also serves as a virus movement protein that transports its cargos to plasmodesmata for cell-to-cell spread via an endocytic recycling pathway []. |
