| Primary Identifier | IPR033202 | Type | Family |
| Short Name | DDAH2 |
| description | Dimethylarginine dimethylaminohydrolase (DDAH) modulates nitric oxide (NO) synthesis via metabolizing asymmetric dimethylarginine (ADMA), an endogenous NO synthase (NOS) inhibitor. Two isoforms of human dimethylarginine dimethylaminohydrolase exist, DDAH1 and DDAH2, with distinct tissue distributions. DDAH 1 predominates in tissues that express neuronal NOS []. DDAH2 expression predominates in highly vascularized tissues that express the endothelial NOS isoform and in immune tissues that can express iNOS [, ]. |
